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Target
ADP-ribosylation factor GTPase-activating protein 1
Ligand
BDBM95196
Substrate
n/a
IC50
>164739±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response screening assay to identify inhibitors of ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1) PubChem Bioassay (2012)[AID] 
Target
Name:
ADP-ribosylation factor GTPase-activating protein 1
Synonyms:
ARFG1_RAT | Arf1gap | Arfgap1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45436.38
Organism:
Rattus norvegicus
Description:
gi_21489979
Residue:
415
Sequence:
MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKFREFLEAQDDYEPSWSLQDKYSSRAAALFRDKVATLAEGKEWSLESSPAQNWTPPQPKTLQFTAHRPAGQPQNVTTSGDKAFEDWLNDDLGSYQGAQENRYVGFGNTVPPQKREDDFLNSAMSSLYSGWSSFTTGASKFASAAKEGATKFGSQASQKASELGHSLNENVLKPAQEKVKEGRIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEDTSDRPLEGHSYQNSSGDNSQNSTIDQSFWETFGSAEPPKAKSPSSDSWTCADASTGRRSSDSWDIWGSGSASNNKNSNSDGWESWEGASGEGRAKATKKAAPSTAADEGWDNQNW
  
Inhibitor
Name:
BDBM95196
Synonyms:
5-(2,5-dichlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furamide | 5-(2,5-dichlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furancarboxamide | 5-(2,5-dichlorophenyl)-N-[4-(morpholin-4-ylmethyl)phenyl]furan-2-carboxamide | 5-(2,5-dichlorophenyl)-N-[4-(morpholinomethyl)phenyl]-2-furamide | 5-[2,5-bis(chloranyl)phenyl]-N-[4-(morpholin-4-ylmethyl)phenyl]furan-2-carboxamide | MLS000594103 | SMR000143162 | cid_2043476
Type:
Small organic molecule
Emp. Form.:
C22H20Cl2N2O3
Mol. Mass.:
431.312
SMILES:
Clc1ccc(Cl)c(c1)-c1ccc(o1)C(=O)Nc1ccc(CN2CCOCC2)cc1
Structure:
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