Reaction Details Report a problem with these data
Target
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM95371
Substrate
n/a
IC50
97459±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2013)[AID] 
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
  
Inhibitor
Name:
BDBM95371
Synonyms:
(4-Oxo-2-{[(E)-3-phenyl-prop-2-en-(E)-ylidene]-hydrazono}-thiazolidin-5-yl)-acetic acid | 2-[4-keto-2-[(N'E)-N'-[(E)-3-phenylprop-2-enylidene]hydrazino]-2-thiazolin-5-yl]acetic acid | 2-[4-oxidanylidene-2-[(2E)-2-[(E)-3-phenylprop-2-enylidene]hydrazinyl]-1,3-thiazol-5-yl]ethanoic acid | 2-[4-oxo-2-[(2E)-2-[(E)-3-phenylprop-2-enylidene]hydrazinyl]-1,3-thiazol-5-yl]acetic acid | 2-[4-oxo-2-[(2E)-2-[(E)-3-phenylprop-2-enylidene]hydrazinyl]-5-thiazolyl]acetic acid | MLS000589139 | SMR000219756 | cid_16428363
Type:
Small organic molecule
Emp. Form.:
C14H13N3O3S
Mol. Mass.:
303.336
SMILES:
OC(=O)Cc1sc(N=NC=CCc2ccccc2)nc1O |w:7.6,10.10|
Structure:
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