Reaction Details
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Report a problem with these dataTarget
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM95394
Substrate
n/a
IC50
85543±n/a nM
Citation
PubChem, PC Absorbance-based biochemical high throughput dose response assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
Inhibitor
Name:
BDBM95394
Synonyms:
3-(1-{[3-(6-methoxy-2-naphthyl)-1H-pyrazol-4-yl]methyl}pyrrolidin-2-yl)-4-methyl-1,2,5-oxadiazole | 3-[1-[[5-(6-methoxy-2-naphthalenyl)-1H-pyrazol-4-yl]methyl]-2-pyrrolidinyl]-4-methyl-1,2,5-oxadiazole | 3-[1-[[5-(6-methoxy-2-naphthyl)-1H-pyrazol-4-yl]methyl]pyrrolidin-2-yl]-4-methyl-furazan | 3-[1-[[5-(6-methoxynaphthalen-2-yl)-1H-pyrazol-4-yl]methyl]pyrrolidin-2-yl]-4-methyl-1,2,5-oxadiazole | MLS000734896 | SMR000316526 | cid_16190042
Type:
Small organic molecule
Emp. Form.:
C22H23N5O2
Mol. Mass.:
389.4503
SMILES:
COc1ccc2cc(ccc2c1)-c1n[nH]cc1CN1CCCC1c1nonc1C
Structure:
