Reaction Details
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Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM95426
Substrate
n/a
IC50
93588±n/a nM
Citation
PubChem, PC Absorbance-based biochemical high throughput dose response assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
Inhibitor
Name:
BDBM95426
Synonyms:
2-(2-keto-8-methyl-4-phenyl-chromen-7-yl)oxy-N,N-dimethyl-acetamide | MLS001173230 | N,N-dimethyl-2-(8-methyl-2-oxidanylidene-4-phenyl-chromen-7-yl)oxy-ethanamide | N,N-dimethyl-2-(8-methyl-2-oxo-4-phenylchromen-7-yl)oxyacetamide | N,N-dimethyl-2-[(8-methyl-2-oxo-4-phenyl-1-benzopyran-7-yl)oxy]acetamide | SMR000539067 | cid_701655
Type:
Small organic molecule
Emp. Form.:
C20H19NO4
Mol. Mass.:
337.3692
SMILES:
CN(C)C(=O)COc1ccc2c(cc(=O)oc2c1C)-c1ccccc1
Structure:
