Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 5 group A member 2
Ligand
BDBM95624
Substrate
n/a
IC50
3117±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) PubChem Bioassay (2013)[AID] 
Target
Name:
Nuclear receptor subfamily 5 group A member 2
Synonyms:
Alpha-1-fetoprotein transcription factor | B1-binding factor | B1F | CPF | CYP7A promoter-binding factor | FTF | Hepatocytic transcription factor | LRH-1 | Liver Receptor Homolog 1 | NR5A2 | NR5A2_HUMAN | Nuclear receptor subfamily 5 group A member 2 | hB1F | nuclear receptor subfamily 5 group A member 2 isoform 2
Type:
Nuclear Hormone Receptor
Mol. Mass.:
61341.37
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
541
Sequence:
MSSNSDTGDLQESLKHGLTPIGAGLPDRHGSPIPARGRLVMLPKVETEALGLARSHGEQGQMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKRA
  
Inhibitor
Name:
BDBM95624
Synonyms:
2,4-dihydroxybenzoic acid [2-[4-[2-(2,4-dihydroxybenzoyl)oxyacetyl]piperazino]-2-keto-ethyl] ester | 2,4-dihydroxybenzoic acid [2-[4-[2-[(2,4-dihydroxyphenyl)-oxomethoxy]-1-oxoethyl]-1-piperazinyl]-2-oxoethyl] ester | MLS001160749 | SMR000707481 | [2-[4-[2-(2,4-dihydroxybenzoyl)oxyacetyl]piperazin-1-yl]-2-oxoethyl] 2,4-dihydroxybenzoate | [2-[4-[2-[2,4-bis(oxidanyl)phenyl]carbonyloxyethanoyl]piperazin-1-yl]-2-oxidanylidene-ethyl] 2,4-bis(oxidanyl)benzoate | cid_24687847
Type:
Small organic molecule
Emp. Form.:
C22H22N2O10
Mol. Mass.:
474.4175
SMILES:
Oc1ccc(C(=O)OCC(=O)N2CCN(CC2)C(=O)COC(=O)c2ccc(O)cc2O)c(O)c1
Structure:
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