Reaction Details
Report a problem with these data
Report a problem with these dataTarget
Tegument protein VP16
Ligand
BDBM95680
Substrate
n/a
IC50
>35878±n/a nM
Citation
PubChem, PC Counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
Tegument protein VP16
Synonyms:
Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16
Type:
PROTEIN
Mol. Mass.:
54325.13
Organism:
Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1)
Description:
EBI_100271
Residue:
490
Sequence:
MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAALFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYVPERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALYRYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILWAAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIREHLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMREHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSLGDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFTDALGIDEYGG
Inhibitor
Name:
BDBM95680
Synonyms:
MLS000097457 | N-(2-methoxyphenyl)-4-[2-[(1-methyl-1,2,3,4-tetrazol-5-yl)sulfanyl]ethanoylamino]benzamide | N-(2-methoxyphenyl)-4-[[2-(1-methyltetrazol-5-yl)sulfanylacetyl]amino]benzamide | N-(2-methoxyphenyl)-4-[[2-[(1-methyl-5-tetrazolyl)thio]-1-oxoethyl]amino]benzamide | N-(2-methoxyphenyl)-4-[[2-[(1-methyltetrazol-5-yl)thio]acetyl]amino]benzamide | SMR000067744 | cid_2094416
Type:
Small organic molecule
Emp. Form.:
C18H18N6O3S
Mol. Mass.:
398.439
SMILES:
COc1ccccc1NC(=O)c1ccc(NC(=O)CSc2nnnn2C)cc1
Structure:
