Target
Tegument protein VP16
Ligand
BDBM95473
Substrate
n/a
IC50
>35861±n/a nM
Citation
 PubChem, PC Counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay (2013)[AID] 
Target
Name:
Tegument protein VP16
Synonyms:
Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16
Type:
PROTEIN
Mol. Mass.:
54325.13
Organism:
Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1)
Description:
EBI_100271
Residue:
490
Sequence:
MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAALFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYVPERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALYRYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILWAAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIREHLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMREHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSLGDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFTDALGIDEYGG
  
Inhibitor
Name:
BDBM95473
Synonyms:
4-[[2-[4-(4-chlorophenyl)-1-piperazinyl]-1-oxoethyl]amino]benzoic acid methyl ester | 4-[[2-[4-(4-chlorophenyl)piperazino]acetyl]amino]benzoic acid methyl ester | MLS000047398 | SMR000033409 | cid_3241786 | methyl 4-({[4-(4-chlorophenyl)piperazin-1-yl]acetyl}amino)benzoate | methyl 4-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethanoylamino]benzoate | methyl 4-[[2-[4-(4-chlorophenyl)piperazin-1-yl]acetyl]amino]benzoate
Type:
Small organic molecule
Emp. Form.:
C20H22ClN3O3
Mol. Mass.:
387.86
SMILES:
COC(=O)c1ccc(NC(=O)CN2CCN(CC2)c2ccc(Cl)cc2)cc1
Structure:
Search PDB for entries with ligand similarity: