Reaction Details
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Report a problem with these dataTarget
Tegument protein VP16
Ligand
BDBM95482
Substrate
n/a
IC50
>35871±n/a nM
Citation
PubChem, PC Counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
Tegument protein VP16
Synonyms:
Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16
Type:
PROTEIN
Mol. Mass.:
54325.13
Organism:
Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1)
Description:
EBI_100271
Residue:
490
Sequence:
MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAALFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYVPERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALYRYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILWAAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIREHLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMREHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSLGDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFTDALGIDEYGG
Inhibitor
Name:
BDBM95482
Synonyms:
4-[5-(2-methoxyphenoxy)-1,2,3,4-tetrazol-1-yl]benzamide | 4-[5-(2-methoxyphenoxy)-1-tetrazolyl]benzamide | 4-[5-(2-methoxyphenoxy)-1H-tetrazol-1-yl]benzamide | 4-[5-(2-methoxyphenoxy)tetrazol-1-yl]benzamide | MLS000538322 | SMR000144359 | cid_935238
Type:
Small organic molecule
Emp. Form.:
C15H13N5O3
Mol. Mass.:
311.2954
SMILES:
COc1ccccc1Oc1nnnn1-c1ccc(cc1)C(N)=O
Structure:
