Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM94952
Substrate
n/a
IC50
5490±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM94952
Synonyms:
2-[4-(2-fluorophenyl)-1-piperazinyl]-1-(1H-indol-6-yl)ethanone | 2-[4-(2-fluorophenyl)piperazin-1-yl]-1-(1H-indol-6-yl)ethanone | 2-[4-(2-fluorophenyl)piperazino]-1-(1H-indol-6-yl)ethanone | MLS000118271 | SMR000095215 | cid_5309171
Type:
Small organic molecule
Emp. Form.:
C20H20FN3O
Mol. Mass.:
337.3907
SMILES:
Fc1ccccc1N1CCN(CC(=O)c2ccc3cc[nH]c3c2)CC1
Structure:
Search PDB for entries with ligand similarity: