Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM95035
Substrate
n/a
IC50
13700±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM95035
Synonyms:
2-(4-methylphenyl)-N-(3-pyridinylmethyl)-4-quinazolinamine | 2-(4-methylphenyl)-N-(pyridin-3-ylmethyl)quinazolin-4-amine | MLS000550241 | Pyridin-3-ylmethyl-(2-p-tolyl-quinazolin-4-yl)-amine | SMR000178038 | [2-(p-tolyl)quinazolin-4-yl]-(3-pyridylmethyl)amine | cid_2790953
Type:
Small organic molecule
Emp. Form.:
C21H18N4
Mol. Mass.:
326.3944
SMILES:
Cc1ccc(cc1)-c1nc(NCc2cccnc2)c2ccccc2n1
Structure:
Search PDB for entries with ligand similarity: