Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM94882
Substrate
n/a
IC50
13000±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay (2013)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM94882
Synonyms:
(4-isopropylbenzyl)-[2-(2-methoxyethylamino)thieno[3,2-d]pyrimidin-4-yl]amine | 2-N-(2-methoxyethyl)-4-N-[(4-propan-2-ylphenyl)methyl]thieno[3,2-d]pyrimidine-2,4-diamine | MLS003122930 | N2-(2-methoxyethyl)-N4-[(4-propan-2-ylphenyl)methyl]thieno[3,2-d]pyrimidine-2,4-diamine | SMR001277937 | cid_46943004
Type:
Small organic molecule
Emp. Form.:
C19H24N4OS
Mol. Mass.:
356.485
SMILES:
COCCNc1nc(NCc2ccc(cc2)C(C)C)c2sccc2n1
Structure:
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