Reaction Details Report a problem with these data
Target
RecBCD enzyme subunit RecD
Ligand
BDBM94482
Substrate
n/a
IC50
85234±n/a nM
Citation
 PubChem, PC Absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay (2013)[AID] 
Target
Name:
RecBCD enzyme subunit RecD
Synonyms:
RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
66906.68
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130723
Residue:
608
Sequence:
MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGLAALFSSRE
  
Inhibitor
Name:
BDBM94482
Synonyms:
4-(4,5-Dimethyl-oxazol-2-ylamino)-benzenesulfonamide | 4-[(4,5-dimethyl-1,3-oxazol-2-yl)amino]benzenesulfonamide | 4-[(4,5-dimethyl-2-oxazolyl)amino]benzenesulfonamide | 4-[(4,5-dimethyloxazol-2-yl)amino]benzenesulfonamide | MLS000029282 | SMR000009090 | cid_648308
Type:
Small organic molecule
Emp. Form.:
C11H13N3O3S
Mol. Mass.:
267.304
SMILES:
Cc1nc(Nc2ccc(cc2)S(N)(=O)=O)oc1C
Structure:
Search PDB for entries with ligand similarity: