Reaction Details Report a problem with these data
Target
RecBCD enzyme subunit RecD
Ligand
BDBM96249
Substrate
n/a
IC50
>118684±n/a nM
Citation
 PubChem, PC Absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay (2013)[AID] 
Target
Name:
RecBCD enzyme subunit RecD
Synonyms:
RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
66906.68
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130723
Residue:
608
Sequence:
MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGLAALFSSRE
  
Inhibitor
Name:
BDBM96249
Synonyms:
(4,6-Dimethyl-1H-pyrazolo[3,4-b]pyridin-3-yl)-morpholin-4-yl-diazene | MLS000567506 | N-[(Z)-(4,6-dimethyl-3-pyrazolo[3,4-b]pyridinylidene)amino]-4-morpholinamine | N-[(Z)-(4,6-dimethylpyrazolo[3,4-b]pyridin-3-ylidene)amino]morpholin-4-amine | SMR000175406 | [(Z)-(4,6-dimethylpyrazolo[3,4-b]pyridin-3-ylidene)amino]-morpholino-amine | cid_9566722
Type:
Small organic molecule
Emp. Form.:
C12H16N6O
Mol. Mass.:
260.295
SMILES:
Cc1cc(C)c2c(N=NN3CCOCC3)[nH]nc2n1 |w:8.8|
Structure:
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