Reaction Details
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Report a problem with these dataTarget
T cell receptor alpha variable 4
Ligand
BDBM40991
Substrate
n/a
IC50
11298±n/a nM
Citation
PubChem, PC Fluorescence-based biochemical primary high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
T cell receptor alpha variable 4
Synonyms:
TCRAV4S1 | TRAV4 | TVA4_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12216.28
Organism:
Homo sapiens (Human)
Description:
A0A0B4J268
Residue:
109
Sequence:
MRQVARVIVFLTLSTLSLAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGD
Inhibitor
Name:
BDBM40991
Synonyms:
5,6-bis(2-furanyl)-4-furo[2,3-d]pyrimidinamine | 5,6-bis(furan-2-yl)furo[2,3-d]pyrimidin-4-amine | MLS000107834 | SMR000103798 | [5,6-bis(2-furyl)furo[2,3-d]pyrimidin-4-yl]amine | cid_704725
Type:
Small organic molecule
Emp. Form.:
C14H9N3O3
Mol. Mass.:
267.2396
SMILES:
Nc1ncnc2oc(-c3ccco3)c(-c3ccco3)c12
Structure:
