Reaction Details Report a problem with these data
Target
T cell receptor alpha variable 4
Ligand
BDBM81248
Substrate
n/a
IC50
18809±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical primary high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe PubChem Bioassay (2013)[AID] 
Target
Name:
T cell receptor alpha variable 4
Synonyms:
TCRAV4S1 | TRAV4 | TVA4_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12216.28
Organism:
Homo sapiens (Human)
Description:
A0A0B4J268
Residue:
109
Sequence:
MRQVARVIVFLTLSTLSLAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGD
  
Inhibitor
Name:
BDBM81248
Synonyms:
7-[2-(3,5-dibromo-4-hydroxy-phenyl)ethylamino]quinoline-5,8-quinone | 7-[2-(3,5-dibromo-4-hydroxyphenyl)ethylamino]quinoline-5,8-dione | 7-[2-[3,5-bis(bromanyl)-4-oxidanyl-phenyl]ethylamino]quinoline-5,8-dione | MLS002702211 | SMR001565774 | cid_381594
Type:
Small organic molecule
Emp. Form.:
C17H12Br2N2O3
Mol. Mass.:
452.097
SMILES:
Oc1cc(N=CCc2cc(Br)c(O)c(Br)c2)c(O)c2ncccc12 |w:4.3|
Structure:
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