Reaction Details Report a problem with these data
Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96661
Substrate
n/a
EC50
>29910±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 agonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | guanine nucleotide-binding protein subunit alpha-15
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96661
Synonyms:
3-methylthiophene-2-carbaldehyde (5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)hydrazone | 5-chloranyl-4-[(2Z)-2-[(3-methylthiophen-2-yl)methylidene]hydrazinyl]-1H-pyridazin-6-one | 5-chloro-4-[(2Z)-2-[(3-methyl-2-thiophenyl)methylidene]hydrazinyl]-1H-pyridazin-6-one | 5-chloro-4-[(2Z)-2-[(3-methylthiophen-2-yl)methylidene]hydrazinyl]-1H-pyridazin-6-one | 5-chloro-4-[(N'Z)-N'-[(3-methyl-2-thienyl)methylene]hydrazino]-1H-pyridazin-6-one | MLS000682989 | SMR000313072 | cid_5941937
Type:
Small organic molecule
Emp. Form.:
C10H9ClN4OS
Mol. Mass.:
268.723
SMILES:
Cc1ccsc1CN=Nc1cn[nH]c(=O)c1Cl |w:8.9|
Structure:
Search PDB for entries with ligand similarity: