Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM96660
Substrate
n/a
IC50
1256±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response. PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM96660
Synonyms:
4-[(1-tert-amyltetrazol-5-yl)-(3,4-dihydro-1H-isoquinolin-2-yl)methyl]phenol;hydrochloride | 4-[3,4-dihydro-1H-isoquinolin-2-yl-[1-(2-methylbutan-2-yl)-1,2,3,4-tetrazol-5-yl]methyl]phenol;hydrochloride | 4-[3,4-dihydro-1H-isoquinolin-2-yl-[1-(2-methylbutan-2-yl)-5-tetrazolyl]methyl]phenol;hydrochloride | 4-[3,4-dihydro-1H-isoquinolin-2-yl-[1-(2-methylbutan-2-yl)tetrazol-5-yl]methyl]phenol;hydrochloride | MLS000715238 | SMR000275217 | cid_16187406
Type:
Small organic molecule
Emp. Form.:
C22H27N5O
Mol. Mass.:
377.4827
SMILES:
CCC(C)(C)n1nnnc1C(N1CCc2ccccc2C1)c1ccc(O)cc1
Structure:
Search PDB for entries with ligand similarity: