Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM96887
Substrate
n/a
IC50
1200±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response. PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM96887
Synonyms:
(2S)-1-[(2S)-2-benzamido-3-methyl-1-oxobutyl]-N-[2-(2-chlorophenyl)ethyl]-2-pyrrolidinecarboxamide | (2S)-1-[(2S)-2-benzamido-3-methyl-butanoyl]-N-[2-(2-chlorophenyl)ethyl]pyrrolidine-2-carboxamide | (2S)-1-[(2S)-2-benzamido-3-methylbutanoyl]-N-[2-(2-chlorophenyl)ethyl]pyrrolidine-2-carboxamide | MLS003777926 | SMR002440906 | cid_53361928
Type:
Small organic molecule
Emp. Form.:
C25H30ClN3O3
Mol. Mass.:
455.977
SMILES:
CC(C)[C@H](NC(=O)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)NCCc1ccccc1Cl
Structure:
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