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Target
Trace amine-associated receptor 1
Ligand
BDBM96569
Substrate
n/a
EC50
2594±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high throughput dose response assay to identify agonists of the human trace amine associated receptor 1 (TAAR1) PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM96569
Synonyms:
6-(3,4-dihydro-1H-isoquinolin-2-yl)-3-(2-methylphenyl)-1H-pyrimidine-2,4-dione | 6-(3,4-dihydro-1H-isoquinolin-2-yl)-3-(o-tolyl)uracil | 6-(3,4-dihydroisoquinolin-2(1H)-yl)-3-(2-methylphenyl)pyrimidine-2,4(1H,3H)-dione | MLS000045905 | SMR000028281 | cid_3243102
Type:
Small organic molecule
Emp. Form.:
C20H19N3O2
Mol. Mass.:
333.3838
SMILES:
Cc1ccccc1-n1c(=O)cc([nH]c1=O)N1CCc2ccccc2C1 |(4.41,.74,;4.41,-.8,;3.08,-1.57,;3.08,-3.11,;4.41,-3.88,;5.75,-3.11,;5.75,-1.57,;7.08,-.8,;8.41,-1.57,;8.41,-3.11,;9.75,-.8,;9.75,.74,;8.41,1.51,;7.08,.74,;5.75,1.51,;11.08,1.51,;11.08,3.05,;12.42,3.82,;13.75,3.05,;15.13,3.88,;16.52,3.09,;16.52,1.48,;15.13,.69,;13.75,1.51,;12.42,.74,)|
Structure:
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