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Target
Trace amine-associated receptor 1
Ligand
BDBM34843
Substrate
n/a
EC50
3091±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high throughput dose response assay to identify agonists of the human trace amine associated receptor 1 (TAAR1) PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM34843
Synonyms:
(1-hydroxy-5-nitro-spiro[benzimidazole-2,1'-cyclohexane]-4-ylidene)-phenethyl-amine | 1-hydroxy-5-nitro-N-(2-phenylethyl)-4-spiro[benzimidazole-2,1'-cyclohexane]imine | 1-hydroxy-5-nitro-N-(2-phenylethyl)spiro[benzimidazole-2,1'-cyclohexane]-4-imine | 5-nitro-1-oxidanyl-N-(2-phenylethyl)spiro[benzimidazole-2,1'-cyclohexane]-4-imine | 5-nitro-N-(2-phenylethyl)spiro[benzimidazole-2,1'-cyclohexan]-4-amine 1-oxide | MLS000723855 | SMR000305450 | cid_16001809
Type:
Small organic molecule
Emp. Form.:
C20H22N4O3
Mol. Mass.:
366.4137
SMILES:
[O-][N+](=O)c1ccc2c(NC3(CCCCC3)[N+]2=O)c1[N-]CCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: