Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM96813
Substrate
n/a
EC50
4113±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high throughput dose response assay to identify agonists of the human trace amine associated receptor 1 (TAAR1) PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM96813
Synonyms:
2-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-2-oxidanylidene-ethyl]sulfanyl-1-(2-methylpropyl)-6-oxidanyl-pyrimidin-4-one | 2-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-2-oxoethyl]sulfanyl-6-hydroxy-1-(2-methylpropyl)pyrimidin-4-one | 2-[[2-(3,4-dihydro-1H-isoquinolin-2-yl)-2-keto-ethyl]thio]-6-hydroxy-1-isobutyl-pyrimidin-4-one | 2-[[2-(3,4-dihydro-1H-isoquinolin-2-yl)-2-oxoethyl]thio]-6-hydroxy-1-(2-methylpropyl)-4-pyrimidinone | MLS002252971 | SMR001315304 | cid_16275304
Type:
Small organic molecule
Emp. Form.:
C19H23N3O3S
Mol. Mass.:
373.469
SMILES:
CC(C)Cn1c(SCC(=O)N2CCc3ccccc3C2)nc(O)cc1=O
Structure:
Search PDB for entries with ligand similarity: