Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM96912
Substrate
n/a
EC50
10036±n/a nM
Citation
 PubChem, PC Counterscreen for antagonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify TAAR1 Agonists PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM96912
Synonyms:
7-(4-fluorophenyl)-4-(4-methyl-1-piperazinyl)-5-phenylpyrrolo[2,3-d]pyrimidine | 7-(4-fluorophenyl)-4-(4-methylpiperazin-1-yl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine | 7-(4-fluorophenyl)-4-(4-methylpiperazin-1-yl)-5-phenyl-pyrrolo[2,3-d]pyrimidine | 7-(4-fluorophenyl)-4-(4-methylpiperazin-1-yl)-5-phenylpyrrolo[2,3-d]pyrimidine | 7-(4-fluorophenyl)-4-(4-methylpiperazino)-5-phenyl-pyrrolo[2,3-d]pyrimidine | MLS000622033 | SMR000310960 | cid_1522618
Type:
Small organic molecule
Emp. Form.:
C23H22FN5
Mol. Mass.:
387.4527
SMILES:
CN1CCN(CC1)c1ncnc2n(cc(-c3ccccc3)c12)-c1ccc(F)cc1
Structure:
Search PDB for entries with ligand similarity: