Reaction Details Report a problem with these data
Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96913
Substrate
n/a
IC50
>29906±n/a nM
Citation
 PubChem, PC Counterscreen for antagonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 antagonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | guanine nucleotide-binding protein subunit alpha-15
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96913
Synonyms:
1-(3-benzoyl-6-methoxy-4-quinolinyl)-3-piperidinecarboxylic acid ethyl ester | 1-(3-benzoyl-6-methoxy-4-quinolyl)nipecotic acid ethyl ester | MLS000686677 | SMR000339740 | cid_16195141 | ethyl 1-(3-benzoyl-6-methoxyquinolin-4-yl)piperidine-3-carboxylate | ethyl 1-[6-methoxy-3-(phenylcarbonyl)quinolin-4-yl]piperidine-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C25H26N2O4
Mol. Mass.:
418.4849
SMILES:
CCOC(=O)C1CCCN(C1)c1c(cnc2ccc(OC)cc12)C(=O)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: