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Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96857
Substrate
n/a
IC50
25745±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 antagonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | guanine nucleotide-binding protein subunit alpha-15
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96857
Synonyms:
4-(4-bromophenyl)-1-[2-(2-methoxyphenyl)ethyl]-5-(2-methylpropyl)imidazole;2,2,2-trifluoroacetic acid | 4-(4-bromophenyl)-1-[2-(2-methoxyphenyl)ethyl]-5-(2-methylpropyl)imidazole;2,2,2-tris(fluoranyl)ethanoic acid | 4-(4-bromophenyl)-5-isobutyl-1-(2-methoxyphenethyl)-1H-imidazole | 4-(4-bromophenyl)-5-isobutyl-1-[2-(2-methoxyphenyl)ethyl]imidazole;2,2,2-trifluoroacetic acid | MLS003510330 | SMR002158064 | cid_56588138
Type:
Small organic molecule
Emp. Form.:
C22H25BrN2O
Mol. Mass.:
413.351
SMILES:
COc1ccccc1CCn1cnc(c1CC(C)C)-c1ccc(Br)cc1
Structure:
Search PDB for entries with ligand similarity: