Reaction Details Report a problem with these data
Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96872
Substrate
n/a
IC50
>29877±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 antagonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | guanine nucleotide-binding protein subunit alpha-15
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96872
Synonyms:
(2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-1-oxo-2-[[oxo(thiophen-2-yl)methyl]amino]-3-(3-pyridinyl)propyl]-2-pyrrolidinecarboxamide;2,2,2-trifluoroacetic acid | (2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-3-(3-pyridyl)-2-(2-thenoylamino)propanoyl]pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid | (2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-3-pyridin-3-yl-2-(thiophen-2-ylcarbonylamino)propanoyl]pyrrolidine-2-carboxamide;2,2,2-tris(fluoranyl)ethanoic acid | (2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-3-pyridin-3-yl-2-(thiophene-2-carbonylamino)propanoyl]pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid | MLS003777893 | SMR002440873 | cid_53361891
Type:
Small organic molecule
Emp. Form.:
C26H27ClN4O3S
Mol. Mass.:
511.036
SMILES:
Clc1ccccc1CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cccnc1)NC(=O)c1cccs1
Structure:
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