Reaction Details Report a problem with these data
Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96925
Substrate
n/a
EC50
>29900±n/a nM
Citation
 PubChem, PC Counterscreen for antagonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose reponse assay to identify nonselective Ga16 agonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | guanine nucleotide-binding protein subunit alpha-15
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96925
Synonyms:
2-[(4-methylbenzyl)thio]-N-[5-morpholinosulfonyl-2-(2,2,2-trifluoroethoxy)phenyl]acetamide | 2-[(4-methylphenyl)methylsulfanyl]-N-[5-morpholin-4-ylsulfonyl-2-(2,2,2-trifluoroethoxy)phenyl]acetamide | 2-[(4-methylphenyl)methylsulfanyl]-N-[5-morpholin-4-ylsulfonyl-2-[2,2,2-tris(fluoranyl)ethoxy]phenyl]ethanamide | 2-[(4-methylphenyl)methylthio]-N-[5-(4-morpholinylsulfonyl)-2-(2,2,2-trifluoroethoxy)phenyl]acetamide | MLS002182285 | SMR001271315 | cid_25163212
Type:
Small organic molecule
Emp. Form.:
C22H25F3N2O5S2
Mol. Mass.:
518.57
SMILES:
Cc1ccc(CSCC(=O)Nc2cc(ccc2OCC(F)(F)F)S(=O)(=O)N2CCOCC2)cc1
Structure:
Search PDB for entries with ligand similarity: