Reaction Details Report a problem with these data
Target
Galanin receptor type 3
Ligand
BDBM97081
Substrate
n/a
IC50
260.46±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). PubChem Bioassay (2013)[AID] 
Target
Name:
Galanin receptor type 3
Synonyms:
GALNR3 | GALR3 | GALR3_HUMAN | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39599.97
Organism:
Homo sapiens (Human)
Description:
Galanin R3 GALR3 HUMAN::O60755
Residue:
368
Sequence:
MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
  
Inhibitor
Name:
BDBM97081
Synonyms:
3-(4-amino-3-nitro-phenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one | 3-(4-amino-3-nitrophenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one | 3-(4-azanyl-3-nitro-phenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one | 6-(4-Amino-3-nitro-phenyl)-5-methyl-4,5-dihydro-2H-pyridazin-3-one | MLS000569138 | SMR000175388 | cid_3111187
Type:
Small organic molecule
Emp. Form.:
C11H12N4O3
Mol. Mass.:
248.238
SMILES:
CC1CC(=O)N[N-][C+]1c1ccc(N)c(c1)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: