Reaction Details Report a problem with these data
Target
Galanin receptor type 3
Ligand
BDBM89289
Substrate
n/a
IC50
157.61±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). PubChem Bioassay (2013)[AID] 
Target
Name:
Galanin receptor type 3
Synonyms:
GALNR3 | GALR3 | GALR3_HUMAN | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39599.97
Organism:
Homo sapiens (Human)
Description:
Galanin R3 GALR3 HUMAN::O60755
Residue:
368
Sequence:
MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
  
Inhibitor
Name:
BDBM89289
Synonyms:
4-chloranyl-N-[(4-chlorophenyl)methyl]-2,5-dimethyl-pyrazole-3-carboxamide | 4-chloro-N-(4-chlorobenzyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide | 4-chloro-N-(4-chlorobenzyl)-2,5-dimethyl-pyrazole-3-carboxamide | 4-chloro-N-[(4-chlorophenyl)methyl]-2,5-dimethyl-3-pyrazolecarboxamide | 4-chloro-N-[(4-chlorophenyl)methyl]-2,5-dimethylpyrazole-3-carboxamide | MLS000701132 | SMR000228049 | cid_1231799
Type:
Small organic molecule
Emp. Form.:
C13H13Cl2N3O
Mol. Mass.:
298.168
SMILES:
Cc1nn(C)c(C(=O)NCc2ccc(Cl)cc2)c1Cl
Structure:
Search PDB for entries with ligand similarity: