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Target
Galanin receptor type 3
Ligand
BDBM97178
Substrate
n/a
IC50
502.85±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). PubChem Bioassay (2013)[AID] 
Target
Name:
Galanin receptor type 3
Synonyms:
GALNR3 | GALR3 | GALR3_HUMAN | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39599.97
Organism:
Homo sapiens (Human)
Description:
Galanin R3 GALR3 HUMAN::O60755
Residue:
368
Sequence:
MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
  
Inhibitor
Name:
BDBM97178
Synonyms:
MLS002702299 | SMR001565861 | [3,4,5-triacetyloxy-6-(3,5-dicyano-2-oxidanylidene-4-phenyl-6-sulfanyl-pyridin-1-yl)oxan-2-yl]methyl ethanoate | [3,4,5-triacetyloxy-6-(3,5-dicyano-2-oxo-4-phenyl-6-sulfanylpyridin-1-yl)oxan-2-yl]methyl acetate | acetic acid [3,4,5-triacetoxy-6-(3,5-dicyano-2-keto-6-mercapto-4-phenyl-1-pyridyl)tetrahydropyran-2-yl]methyl ester | acetic acid [3,4,5-triacetyloxy-6-(3,5-dicyano-2-mercapto-6-oxo-4-phenyl-1-pyridinyl)-2-oxanyl]methyl ester | cid_386315
Type:
Small organic molecule
Emp. Form.:
C27H25N3O10S
Mol. Mass.:
583.567
SMILES:
CC(=O)OCC1OC(C(OC(C)=O)C(OC(C)=O)C1OC(C)=O)n1c(S)c(C#N)c(-c2ccccc2)c(C#N)c1=O
Structure:
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