Reaction Details Report a problem with these data
Target
Kallikrein-7
Ligand
BDBM100124
Substrate
n/a
EC50
86401±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM100124
Synonyms:
MLS001031137 | N-cyclopropyl-2-(4-methoxyphenyl)-4-quinolinecarboxamide | N-cyclopropyl-2-(4-methoxyphenyl)cinchoninamide | N-cyclopropyl-2-(4-methoxyphenyl)quinoline-4-carboxamide | SMR000634697 | cid_757621
Type:
Small organic molecule
Emp. Form.:
C20H18N2O2
Mol. Mass.:
318.3691
SMILES:
COc1ccc(cc1)-c1cc(C(=O)NC2CC2)c2ccccc2n1
Structure:
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