Reaction Details Report a problem with these data
Target
Kallikrein-7
Ligand
BDBM100138
Substrate
n/a
EC50
66227±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM100138
Synonyms:
2-bromanyl-N-(6-ethanoyl-1,3-benzodioxol-5-yl)benzenesulfonamide | MLS001220824 | N-(6-Acetyl-benzo[1,3]dioxol-5-yl)-2-bromo-benzenesulfonamide | N-(6-acetyl-1,3-benzodioxol-5-yl)-2-bromo-benzenesulfonamide | N-(6-acetyl-1,3-benzodioxol-5-yl)-2-bromobenzenesulfonamide | SMR000600282 | cid_1448335
Type:
Small organic molecule
Emp. Form.:
C15H12BrNO5S
Mol. Mass.:
398.228
SMILES:
CC(=O)c1cc2OCOc2cc1NS(=O)(=O)c1ccccc1Br
Structure:
Search PDB for entries with ligand similarity: