Reaction Details Report a problem with these data
Target
COUP transcription factor 2
Ligand
BDBM97108
Substrate
n/a
IC50
1969±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2) PubChem Bioassay (2013)[AID] 
Target
Name:
COUP transcription factor 2
Synonyms:
ARP1 | COT2_HUMAN | COUP transcription factor 2 isoform a | NR2F2 | TFCOUP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45583.83
Organism:
Homo sapiens (Human)
Description:
gi_14149746
Residue:
414
Sequence:
MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
  
Inhibitor
Name:
BDBM97108
Synonyms:
MLS001007488 | N-[2-(3,4-dimethoxyphenyl)ethyl]-4-thieno[2,3-d]pyrimidinamine | N-[2-(3,4-dimethoxyphenyl)ethyl]thieno[2,3-d]pyrimidin-4-amine | SMR000352663 | cid_2100093 | homoveratryl(thieno[2,3-d]pyrimidin-4-yl)amine
Type:
Small organic molecule
Emp. Form.:
C16H17N3O2S
Mol. Mass.:
315.39
SMILES:
COc1ccc(CCNc2ncnc3sccc23)cc1OC
Structure:
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