Reaction Details Report a problem with these data
Target
COUP transcription factor 2
Ligand
BDBM76151
Substrate
n/a
IC50
3283±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2) PubChem Bioassay (2013)[AID] 
Target
Name:
COUP transcription factor 2
Synonyms:
ARP1 | COT2_HUMAN | COUP transcription factor 2 isoform a | NR2F2 | TFCOUP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45583.83
Organism:
Homo sapiens (Human)
Description:
gi_14149746
Residue:
414
Sequence:
MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
  
Inhibitor
Name:
BDBM76151
Synonyms:
4-[11-[[(2S)-2-[4-[5-(tert-butoxycarbonylamino)pentyl]triazol-1-yl]-3-hydroxy-propanoyl]amino]undecanoyl]piperazine-1-carboxylic acid tert-butyl ester | 4-[11-[[(2S)-3-hydroxy-2-[4-[5-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]pentyl]-1-triazolyl]-1-oxopropyl]amino]-1-oxoundecyl]-1-piperazinecarboxylic acid tert-butyl ester | Boc-KS | MLS002153745 | SMR001231171 | cid_24983197 | tert-butyl 4-[11-[[(2S)-2-[4-[5-[(2-methylpropan-2-yl)oxycarbonylamino]pentyl]-1,2,3-triazol-1-yl]-3-oxidanyl-propanoyl]amino]undecanoyl]piperazine-1-carboxylate | tert-butyl 4-[11-[[(2S)-3-hydroxy-2-[4-[5-[(2-methylpropan-2-yl)oxycarbonylamino]pentyl]triazol-1-yl]propanoyl]amino]undecanoyl]piperazine-1-carboxylate
Type:
Small organic molecule
Emp. Form.:
C35H63N7O7
Mol. Mass.:
693.9174
SMILES:
CC(C)(C)OC(=O)NCCCCCc1cn(nn1)[C@@H](CO)C(=O)NCCCCCCCCCCC(=O)N1CCN(CC1)C(=O)OC(C)(C)C
Structure:
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