Reaction Details Report a problem with these data
Target
COUP transcription factor 2
Ligand
BDBM89484
Substrate
n/a
IC50
>12.98±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2) PubChem Bioassay (2013)[AID] 
Target
Name:
COUP transcription factor 2
Synonyms:
ARP1 | COT2_HUMAN | COUP transcription factor 2 isoform a | NR2F2 | TFCOUP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45583.83
Organism:
Homo sapiens (Human)
Description:
gi_14149746
Residue:
414
Sequence:
MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
  
Inhibitor
Name:
BDBM89484
Synonyms:
MLS002702998 | Ossamycin | SMR001566807 | cid_5351598
Type:
Small organic molecule
Emp. Form.:
C49H85NO14
Mol. Mass.:
912.1975
SMILES:
[H][C@@]12CC(C)(C)O[C@@]1(O)C[C@]1([H])O[C@]3(CCC[C@H](C[C@H](O)CC)O3)C[C@]([H])(OC(=O)\C=C\[C@@](C)(O)[C@@H](O)[C@H](C)[C@@H](O)[C@H](OC3CCC(C(C)O3)N(C)C)[C@@H](O)[C@](C)(O)CCCCC\C=C/2)[C@@H]1C |c:66,t:32|
Structure:
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