Reaction Details Report a problem with these data
Target
COUP transcription factor 2
Ligand
BDBM100261
Substrate
n/a
IC50
7.64±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2) PubChem Bioassay (2013)[AID] 
Target
Name:
COUP transcription factor 2
Synonyms:
ARP1 | COT2_HUMAN | COUP transcription factor 2 isoform a | NR2F2 | TFCOUP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45583.83
Organism:
Homo sapiens (Human)
Description:
gi_14149746
Residue:
414
Sequence:
MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
  
Inhibitor
Name:
BDBM100261
Synonyms:
MLS002702133 | SMR001565698 | cid_431377
Type:
Small organic molecule
Emp. Form.:
C29H36O11
Mol. Mass.:
560.5895
SMILES:
[H]C12CC3OC(=O)C=CC=CC(=O)OCCC(C)C(OC(C)=O)C(=O)OCC4(CCC5(C)OC5C4O1)C3(C)C21CO1 |TLB:33:34:38:3.2,28:27:38:3.2,26:27:38:3.2,THB:40:38:35.27.34:3.2,4:3:38:35.27.34,39:38:35.27.34:3.2|
Structure:
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