Reaction Details Report a problem with these data
Target
Adenosine receptor A2
Ligand
BDBM108258
Substrate
n/a
Meas. Tech.
Binding Assay
Ki
9113±0.0 nM
Citation
 Jagtap, P; Szabo, C; Salzman, AL Purine derivatives as adenosine A1 receptor agonists and methods of use thereof US Patent  US8609833 Publication Date 12/17/2013 
Target
Name:
Adenosine receptor A2
Synonyms:
ADORA2A | C9JQD8_HUMAN
Type:
Enzyme
Mol. Mass.:
40112.08
Organism:
Homo sapiens (Human)
Description:
C9JQD8
Residue:
365
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGL
  
Inhibitor
Name:
BDBM108258
Synonyms:
US8609833, 91
Type:
Small organic molecule
Emp. Form.:
C15H20N5O6S
Mol. Mass.:
398.415
SMILES:
O[C@@H]1[C@@H](CS([O-])(=O)=O)O[C@H]([C@@H]1O)n1cnc2c(NC3CCCC3)ncnc12 |r|
Structure:
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