Reaction Details Report a problem with these data
Target
Angiogenin
Ligand
BDBM111444
Substrate
n/a
Meas. Tech.
Inhibition Kinetics with Angiogenin
pH
6±n/a
Ki
4.27e+5± 7e+3 nM
Comments
extracted
Citation
 Debnath, J; Dasgupta, S; Pathak, T Amino and carboxy functionalized modified nucleosides: a potential class of inhibitors for angiogenin. Bioorg Chem 52:56-61 (2014) [PubMed]  Article 
Target
Name:
Angiogenin
Synonyms:
ANG | ANGI_HUMAN | RNASE5
Type:
Protein
Mol. Mass.:
16563.00
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
147
Sequence:
MVMGLGVLLLVFVLGLGLTPPTLAQDNSRYTHFLTQHYDAKPQGRDDRYCESIMRRRGLTSPCKDINTFIHGNKRSIKAICENKNGNPHRENLRISKSSFQVTTCKLHGGSPWPPCQYRATAGFRNVVVACENGLPVHLDQSIFRRP
  
Inhibitor
Name:
BDBM111444
Synonyms:
Ser-aT (Compound 2)
Type:
Small organic moleucle
Emp. Form.:
C13H20N4O6
Mol. Mass.:
328.3211
SMILES:
Cc1cn([C@H]2C[C@@H](NC(=O)C(N)CO)[C@@H](CO)O2)c(=O)[nH]c1=O |r|
Structure:
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