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Target
Mu-type opioid receptor
Ligand
BDBM114605
Substrate
n/a
Meas. Tech.
Late stage Counterscreen for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A)
EC50
92470±n/a nM
Citation
 PubChem, PC Late stage Counterscreen for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A): Luminescence-based cell-based high throughput dose response assay to identify agonists of the mu 1 opioid receptor (OPRM1) PubChem Bioassay (2013)[AID] 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM114605
Synonyms:
2-[4-(2,5-difluorobenzyl)piperazino]pyrimidine | 2-[4-[(2,5-difluorophenyl)methyl]-1-piperazinyl]pyrimidine | 2-[4-[(2,5-difluorophenyl)methyl]piperazin-1-yl]pyrimidine | 2-[4-[[2,5-bis(fluoranyl)phenyl]methyl]piperazin-1-yl]pyrimidine | SR-01000208233 | SR-01000208233-3 | cid_782050
Type:
Small organic molecule
Emp. Form.:
C15H16F2N4
Mol. Mass.:
290.3111
SMILES:
Fc1ccc(F)c(CN2CCN(CC2)c2ncccn2)c1
Structure:
Search PDB for entries with ligand similarity: