Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 2A
Ligand
BDBM45364
Substrate
n/a
Meas. Tech.
Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A)
EC50
76083±n/a nM
Citation
 PubChem, PC Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A): Luminescence-based cell-based high throughput dose response assay for agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) PubChem Bioassay (2013)[AID] 
Target
Name:
5-hydroxytryptamine receptor 2A
Synonyms:
5-HT-2 | 5-HT-2A | 5-hydroxytryptamine receptor 2A | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_MOUSE | Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor | Htr2 | Htr2a | Serotonin 2a (5-HT2a) receptor
Type:
Enzyme
Mol. Mass.:
52843.00
Organism:
Mus musculus (Mouse)
Description:
P35363
Residue:
471
Sequence:
MEILCEDNISLSSIPNSLMQLGDDSRLYPNDFNSRDANTSEASNWTIDAENRTNLSCEGYLPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLSSFSFLPQSSLSSEKLFQRSIHREPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPTLAYKSSQLQVGQKKNSQEDAEPTANDCSMVTLGNQHSEEMCTDNIETVNEKVSCV
  
Inhibitor
Name:
BDBM45364
Synonyms:
MLS000047378 | N-(4-phenoxyphenyl)-2-(4-pyridin-2-ylpiperazin-1-yl)acetamide | N-(4-phenoxyphenyl)-2-(4-pyridin-2-ylpiperazin-1-yl)ethanamide | N-(4-phenoxyphenyl)-2-[4-(2-pyridinyl)-1-piperazinyl]acetamide | N-(4-phenoxyphenyl)-2-[4-(2-pyridyl)piperazino]acetamide | SMR000033389 | cid_3237037
Type:
Small organic molecule
Emp. Form.:
C23H24N4O2
Mol. Mass.:
388.4623
SMILES:
O=C(CN1CCN(CC1)c1ccccn1)Nc1ccc(Oc2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: