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Target
Fibrinogen beta chain [164-491]
Ligand
BDBM114663
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer
IC50
83309±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )] PubChem Bioassay (2013)[AID] 
Target
Name:
Fibrinogen beta chain [164-491]
Synonyms:
Chain E, Fragment Double-D From Human Fibrin | FGB | FIBB_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37647.12
Organism:
Homo sapiens (Human)
Description:
gi_28373962
Residue:
328
Sequence:
DNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFPQQ
  
Inhibitor
Name:
BDBM114663
Synonyms:
3-(1-amino-9,10-dioxoanthracen-2-yl)sulfanylpropanoic acid | 3-[(1-amino-9,10-diketo-2-anthryl)thio]propionic acid | 3-[(1-amino-9,10-dioxo-2-anthracenyl)thio]propanoic acid | 3-[1-azanyl-9,10-bis(oxidanylidene)anthracen-2-yl]sulfanylpropanoic acid | MLS001164928 | SMR000540155 | cid_4356619
Type:
Small organic molecule
Emp. Form.:
C17H13NO4S
Mol. Mass.:
327.354
SMILES:
Nc1c(SCCC(O)=O)ccc2C(=O)c3ccccc3C(=O)c12
Structure:
Search PDB for entries with ligand similarity: