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Target
RNA-editing ligase 1, mitochondrial
Ligand
BDBM128131
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of Trypanosoma brucei RNA editing ligase 1 (TbREL1).
IC50
>96559±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of Trypanosoma brucei RNA editing ligase 1 (TbREL1). PubChem Bioassay (2014)[AID] 
Target
Name:
RNA-editing ligase 1, mitochondrial
Synonyms:
REL1 | RLGM1_TRYBB | Trypanosoma brucei RNA editing ligase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52299.36
Organism:
Trypanosoma brucei brucei
Description:
gi_342179211
Residue:
469
Sequence:
MQLQRLGAPLLKRLVGGCIRQSTAPIMPCVVVSGSGVFLTPVRTYMPLPNDQSDFSPYIEIDLPSESRIQSLHKSGLAAQEWVACEKVHGTNFGIYLINQGDHEVVRFAKRSGIMDPNENFFGYHILIDEFTAQIRILNDLLKQKYGLSRVGRLVLNGELFGAKYKHPLVPKSEKWCTLPNGKKFPIAGVQIQREPFPQYSPELHFFAFDIKYSVSGAEEDFVLLGYDEFVEFSSKVPNLLYARALVRGTLDECLAFDVENFMTPLPALLGLGNYPLEGNLAEGVVIRHVRRGDPAVEKHNVSTIIKLRCSSFMELKHPGKQKELKETFIDTVRSGALRRVRGNVTVISDSMLPQVEAAANDLLLNNVSDGRLSNVLSKIGREPLLSGEVSQVDVVLMLAKDALKDFLKEVDSLVLNTTLAFRKLLITNVYFESKRLVEQKWKELMQEEAAAQSEAIPPLSPAAPTKGE
  
Inhibitor
Name:
BDBM128131
Synonyms:
1-[2-[3-(4-benzylpiperidin-1-yl)propoxy]phenyl]propan-1-one;oxalic acid | 1-[2-[3-(4-benzylpiperidino)propoxy]phenyl]propan-1-one;oxalic acid | 1-{2-[3-(4-benzyl-1-piperidinyl)propoxy]phenyl}-1-propanone oxalate | MLS001001886 | SMR000498387 | cid_2976907 | ethanedioic acid;1-[2-[3-[4-(phenylmethyl)piperidin-1-yl]propoxy]phenyl]propan-1-one | oxalic acid;1-[2-[3-[4-(phenylmethyl)-1-piperidinyl]propoxy]phenyl]-1-propanone
Type:
Small organic molecule
Emp. Form.:
C26H33NO6
Mol. Mass.:
455.5433
SMILES:
OC(=O)C(O)=O.CCC(=O)c1ccccc1OCCCN1CCC(Cc2ccccc2)CC1
Structure:
Search PDB for entries with ligand similarity: