Reaction Details Report a problem with these data
Target
Transthyretin
Ligand
BDBM128202
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription
EC50
>167158±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription PubChem Bioassay (2014)[AID] 
Target
Name:
Transthyretin
Synonyms:
ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR)
Type:
Enzyme
Mol. Mass.:
15884.31
Organism:
Homo sapiens (Human)
Description:
P02766
Residue:
147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
  
Inhibitor
Name:
BDBM128202
Synonyms:
4-(2-pyridinylthio)benzofuro[3,2-d]pyrimidine | 4-(2-pyridylthio)benzofuro[3,2-d]pyrimidine | 4-(Pyridin-2-ylsulfanyl)-benzo[4,5]furo[3,2-d]pyrimidine | 4-pyridin-2-ylsulfanyl-[1]benzofuro[3,2-d]pyrimidine | MLS000071568 | SMR000010569 | cid_624350
Type:
Small organic molecule
Emp. Form.:
C15H9N3OS
Mol. Mass.:
279.316
SMILES:
S(c1ccccn1)c1ncnc2c3ccccc3oc12
Structure:
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