Target
Transthyretin
Ligand
BDBM128206
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription
EC50
>167158±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription PubChem Bioassay (2014)[AID] 
Target
Name:
Transthyretin
Synonyms:
ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR)
Type:
Enzyme
Mol. Mass.:
15884.31
Organism:
Homo sapiens (Human)
Description:
P02766
Residue:
147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
  
Inhibitor
Name:
BDBM128206
Synonyms:
2,3-dihydroindol-1-yl-(5-methyl-2-phenyl-3-pyrazolyl)methanone | 2,3-dihydroindol-1-yl-(5-methyl-2-phenyl-pyrazol-3-yl)methanone | 2,3-dihydroindol-1-yl-(5-methyl-2-phenylpyrazol-3-yl)methanone | MLS000117799 | SMR000094747 | cid_5308164 | indolin-1-yl-(5-methyl-2-phenyl-pyrazol-3-yl)methanone
Type:
Small organic molecule
Emp. Form.:
C19H17N3O
Mol. Mass.:
303.3578
SMILES:
Cc1cc(C(=O)N2CCc3ccccc23)n(n1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: