Reaction Details Report a problem with these data
Target
Transthyretin
Ligand
BDBM96956
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription
EC50
>167158±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription PubChem Bioassay (2014)[AID] 
Target
Name:
Transthyretin
Synonyms:
ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR)
Type:
Enzyme
Mol. Mass.:
15884.31
Organism:
Homo sapiens (Human)
Description:
P02766
Residue:
147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
  
Inhibitor
Name:
BDBM96956
Synonyms:
4-(1,3-benzothiazol-2-yl)-N-(5-methyl-1,3-thiazol-2-yl)butanamide | 4-(1,3-benzothiazol-2-yl)-N-(5-methyl-2-thiazolyl)butanamide | 4-(1,3-benzothiazol-2-yl)-N-(5-methylthiazol-2-yl)butyramide | MLS000568842 | SMR000154827 | cid_2445782
Type:
Small organic molecule
Emp. Form.:
C15H15N3OS2
Mol. Mass.:
317.429
SMILES:
Cc1cnc(NC(=O)CCCc2nc3ccccc3s2)s1
Structure:
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