Target
Transthyretin
Ligand
BDBM128212
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription
EC50
>167158±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription PubChem Bioassay (2014)[AID] 
Target
Name:
Transthyretin
Synonyms:
ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR)
Type:
Enzyme
Mol. Mass.:
15884.31
Organism:
Homo sapiens (Human)
Description:
P02766
Residue:
147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
  
Inhibitor
Name:
BDBM128212
Synonyms:
4-[(5-benzyl-1,3,4-oxadiazol-2-yl)sulfanylmethyl]benzoic acid | 4-[[(5-benzyl-1,3,4-oxadiazol-2-yl)thio]methyl]benzoic acid | 4-[[5-(phenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]benzoic acid | 4-[[[5-(phenylmethyl)-1,3,4-oxadiazol-2-yl]thio]methyl]benzoic acid | 4-{[(5-benzyl-1,3,4-oxadiazol-2-yl)thio]methyl}benzoic acid | MLS000531511 | SMR000136489 | cid_1249904
Type:
Small organic molecule
Emp. Form.:
C17H14N2O3S
Mol. Mass.:
326.37
SMILES:
OC(=O)c1ccc(CSc2nnc(Cc3ccccc3)o2)cc1
Structure:
Search PDB for entries with ligand similarity: