Target
Transthyretin
Ligand
BDBM66579
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription
EC50
>167158±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription PubChem Bioassay (2014)[AID] 
Target
Name:
Transthyretin
Synonyms:
ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR)
Type:
Enzyme
Mol. Mass.:
15884.31
Organism:
Homo sapiens (Human)
Description:
P02766
Residue:
147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
  
Inhibitor
Name:
BDBM66579
Synonyms:
1-(2-benzylsulfanyl-4,5-dihydroimidazol-1-yl)-2-phenoxypropan-1-one | 1-[2-(benzylthio)-2-imidazolin-1-yl]-2-phenoxy-propan-1-one | 2-phenoxy-1-[2-(phenylmethylsulfanyl)-4,5-dihydroimidazol-1-yl]propan-1-one | 2-phenoxy-1-[2-(phenylmethylthio)-4,5-dihydroimidazol-1-yl]-1-propanone | MLS000684685 | SMR000323191 | cid_4558613
Type:
Small organic molecule
Emp. Form.:
C19H20N2O2S
Mol. Mass.:
340.439
SMILES:
CC(Oc1ccccc1)C(=O)N1CCN=C1SCc1ccccc1 |c:15|
Structure:
Search PDB for entries with ligand similarity: