Reaction Details Report a problem with these data
Target
Transthyretin
Ligand
BDBM128232
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription
EC50
>167158±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription PubChem Bioassay (2014)[AID] 
Target
Name:
Transthyretin
Synonyms:
ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR)
Type:
Enzyme
Mol. Mass.:
15884.31
Organism:
Homo sapiens (Human)
Description:
P02766
Residue:
147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
  
Inhibitor
Name:
BDBM128232
Synonyms:
3-(3,4-Dimethoxy-phenyl)-5-thiophen-2-yl-[1,2,4]oxadiazole | 3-(3,4-dimethoxyphenyl)-5-(2-thienyl)-1,2,4-oxadiazole | 3-(3,4-dimethoxyphenyl)-5-thiophen-2-yl-1,2,4-oxadiazole | MLS000333489 | SMR000437691 | cid_1221653
Type:
Small organic molecule
Emp. Form.:
C14H12N2O3S
Mol. Mass.:
288.322
SMILES:
COc1ccc(cc1OC)-c1noc(n1)-c1cccs1
Structure:
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