Target
Transthyretin
Ligand
BDBM128235
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription
EC50
>167158±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription PubChem Bioassay (2014)[AID] 
Target
Name:
Transthyretin
Synonyms:
ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR)
Type:
Enzyme
Mol. Mass.:
15884.31
Organism:
Homo sapiens (Human)
Description:
P02766
Residue:
147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
  
Inhibitor
Name:
BDBM128235
Synonyms:
2,5-bis[(dimethylamino)methyl]-1,1,6,6-tetraphenyl-hexane-1,6-diol | 2,5-bis[(dimethylamino)methyl]-1,1,6,6-tetraphenylhexane-1,6-diol | MLS001173677 | SMR000538747 | cid_3781244
Type:
Small organic molecule
Emp. Form.:
C36H44N2O2
Mol. Mass.:
536.7468
SMILES:
CN(C)CC(CCC(CN(C)C)C(O)(c1ccccc1)c1ccccc1)C(O)(c1ccccc1)c1ccccc1
Structure:
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