Reaction Details Report a problem with these data
Target
Transthyretin
Ligand
BDBM94271
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription
EC50
>167158±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription PubChem Bioassay (2014)[AID] 
Target
Name:
Transthyretin
Synonyms:
ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR)
Type:
Enzyme
Mol. Mass.:
15884.31
Organism:
Homo sapiens (Human)
Description:
P02766
Residue:
147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
  
Inhibitor
Name:
BDBM94271
Synonyms:
2-methoxy-5-(3-methyl-1,2-oxazol-5-yl)-N-[(3-methylphenyl)methyl]benzenesulfonamide | 2-methoxy-5-(3-methyl-5-isoxazolyl)-N-[(3-methylphenyl)methyl]benzenesulfonamide | 2-methoxy-N-(3-methylbenzyl)-5-(3-methylisoxazol-5-yl)benzenesulfonamide | MLS001095083 | SMR000630399 | cid_20936139
Type:
Small organic molecule
Emp. Form.:
C19H20N2O4S
Mol. Mass.:
372.438
SMILES:
COc1ccc(cc1S(=O)(=O)NCc1cccc(C)c1)-c1cc(C)no1
Structure:
Search PDB for entries with ligand similarity: