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TargetBiotin ligase
LigandBDBM161470
Substrate/Competitorn/a
Meas. Tech.Enzyme Inhibition Assay
pH8±n/a
Temperature310.15±n/a K
Ki 660±n/a nM
IC50 4000±n/a nM
Commentsextracted
Citation Abell, APolyak, SBooker, GWallace, JSoares da Costa, TJarrad, ATieu, WKeeling, KLPedersen, DSPendini, NWilce, MYap, MY Antimicrobial compounds US Patent US9108978 Publication Date 8/18/2015
More Info.:Get all data from this article,  Assay Method
 
Biotin ligase
Name:Biotin ligase
Synonyms:Biotin protein ligase (BPL)
Type:Protein
Mol. Mass.:37140.09
Organism:Staphylococcus aureus
Description:W8TTE7
Residue:323
Sequence:
MSKYSQDVLQLLYKNKPNYISGQSIAESLNISRTAVKKVIDQLKLEGCKIDSVNHKGHLL
QQLPDIWYQGIIDQYTKSSALFDFSEVYDSIDSTQLAAKKSLVGNQSSFFILSDEQTKGR
GRFNRHWSSSKGQGLWMSVVLRPNVAFSMISKFNLFIALGIRDAIQHFSQDEVKVKWPND
IYIDNGKVCGFLTEMVANNDGIEAIICGIGINLTQQLENFDESIRHRATSIQLHDKNKLD
RYQFLERLLQEIEKRYNQFLTLPFSEIREEYIAASNIWNRTLLFTENDKQFKGQAIDLDY
DGYLIVRDEAGESHRLISADIDF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM161470
NameBDBM161470
Synonyms:US9108978, 4.01
TypeSmall organic molecule
Emp. Form.C21H30N10OS
Mol. Mass.470.594
SMILESNc1ncnc2n(CCCCn3cc(CCCCC[C@@H]4SC[C@@H]5NC(=O)N[C@H]45)nn3)cnc12 |r|
Structure
n/a